Molecular Systems and Nanomaterials for Energy and Health (SyMMES)
Head : Frederic CHANDEZON - Deputies Head : Yoann Roupioz et Thierry Douki

The Symmes laboratory aims to develop basic research on themes with strong societal issue: zero-carbon energy, information and communications technology (ICT), biotechnology and human health. To do this, the Symmes explores the design, synthesis and study of architectures and innovative and original functional materials, guarantees of the relevance of future research proposals from the laboratory. The laboratory is also interested in the reactivity and properties of biomolecules, providing a novel approach to biological questions.


Organigramme :


Workforce :

The Symmes is composed of 47 researchers, 14 technicians and engineers, and 3 managers and administrative assistants (63% from the CEA, 22% from the CNRS and 15% from the University).

The Symmes also hosts about sixty non-permanent researchers (students, PhD students and post-doctoral students.)

The Symmes thanks the Auvergne-Rhône-Alpes region for the award of an ADR 2015-2018 to Natacha HUYNH.


Last update : 02/20 2017 (1148)

CREAB - Head: Arnaud BUHOT
The team CREAB develops its research activities at the interface between physics-chemistry-biology with two principal axes: 1/ the conception, the development and the use of biosensors and/or biochips for the analysis of interactions from the molecular scale up to more complex biological objects ... More »
The chemists and biologists of the CIBEST team (CIBEST stands for " Chemistry-Biology Interface for environment, health and toxicology ")  use complementary approaches to understand the mechanisms involved in the human and environmental toxicity of physical or chemical agents. Our ... More »
CAMPE is a laboratory for fundamental research combining chemists specializing in synthesis, theoreticians specializing in molecular modeling, spectroscopists and specialists of instrumentation. The laboratory undertakes research in chemistry and molecular physical chemistry, focusing on the ... More »
STEP is an interdisciplinary team comprising chemists, physico-chemists, electrochemists and physicists. Our objectives are the control of molecular architectures and complex functionalities, the design of novel performing materials as well as the description and understanding of their physical ... More »
Contact : David Aradilla
Rodrigo Newell has received an award by the Société Chimique de France (SCF - Subdivision Electrochimie) within the framework of his master project conducted at INAC/SyMMES/STEP under the supervision of Dr. Aradilla. The prize is a recognition for his work dealing with the development ... More »
  We have developed arrays of innovative magnetic nanotweezers or “nanojaws” on silicon wafers, by a top-down approach using the fabrication techniques of microelectronics.   The mechanical manipulation of micro- and nanometric objects relies on constantly evolving ... More »
Contact : Stefano Mossa
Veerapandian Ponnuchamy, Ioannis Skarmoutsos, Stefano Mossa - INAC/SYMMES Valentina Vetere - LITEN/DEHT The electrolyte is a crucial component of a Lithium-ion battery. On one side, it affects the rate of the energy release, by controlling the mass transport properties within the cell. It ... More »
An unprecedented detailed description of local cationic sites embedded within a Li-rich (Mn/Ni) layered oxide has been achieved by combining Solid-State Nuclear Magnetic Resonance (MAS-NMR) spectroscopy of the lithium and a statistical model allowing to extract structural information out of the ... More »
Drug targeting is an attractive and powerful therapeutic strategy that is proposed to enhance drug efficacy and to decrease the many side-effects associated with systemic drug therapy. Indeed, it achieves specific drug accumulation in the diseased organ or cells. This strategy is exploited at INAC ... More »
Contact : David ARADILLA
Within the framework of the NEST (Nanowires for Energy STorage) european project (2012 -2016, no. 309143) two teams from INAC (SyMMES/PCI and PhELIQS/SiNAPS), in a tight collaboration with an industrial company (IOLITEC, Heilbronn, Germany) and a technological center (FHG, Freiburg, Germany), have ... More »
Contact : Thierry Douki
Combustion of organic matter (engine exhaust, urban heating, etc.) produces some toxic and carcinogenic compounds known as Polycyclic Aromatic Hydrocarbons (PAH). After metabolization in cells they become reactive and can modify DNA. Numerous work have studied PAH as individual products. The data ... More »
Contact : Stefano Mossa
Confinement at the nano-scale and interaction with interfaces profoundly alter structure and dynamics of water. Grasping the true nature of these modifications at the molecular level is crucial, in contexts as diverse as biology or materials science. In particular, these phenomena are everywhere in ... More »
Contact : Stefano Mossa
Control of heat transport at the nanoscale is crucial for many technologies, including thermoelectricity. We have demonstrated by computer simulation of a toy model, that it is possible to design highly ordered systems with thermal conductivities lower than those of completely disordered structures ... More »
Contact : David Aradilla
Over the past years the rapid and growing demand of miniaturized electronic devices, such as medical implants (neurotransmitters), micro-sensors or micro-mechanical systems, has triggered intensive investigations in the research of new on-chip energy storage units for their integration into such ... More »
To mimic the copper transport protein Ctr1, responsible for copper entrance into cells, several molecular architectures based on the symmetric scaffold, nitrilotriacetic acid (NTA) functionalized with three amino acids bearing thioether side chains were designed. These thioether derivatives form ... More »
Contact : Dmitry Aldakov
Jinhyung Park, a postdoc fellow working at SPrAM/LEMOH and funded by the ANR grant QuePhelec", has been awarded the NanoART monthly prize in February 2015.   NanoART is a Nano Imagery contest sponsored by nRai® and OCSiAl, and organized in Grenoble by the ... More »
Contact : Thierry Douki
While melanin's role is to protect us when exposed to ultraviolet (UV) radiation from the Sun, the molecules used to make it could produce alterations in the DNA. CEA researchers and their international collaborators have observed this antagonistic effect in melanin production chain for several ... More »
Contact : Dorian Gaboriau
The 2014 NanoArt winner is Dorian Gaboriau, a PhD student working at SPrAM/LEMOH and SP2M/SiNaPS and co-funded by DGA and CEA. He was first awarded the monthly prize in October 2014.   NanoART is a Nano Imagery contest sponsored ... More »
Contact : Peter Reiss
Louis Vaure, a PhD student working at SPrAM/LEMOH and co-funded by CEA and DGA, has been awarded the NanoART monthly prize in December 2014.   NanoART is a Nano Imagery contest sponsored by nRai® and organized in Grenoble by the Nanoscience ... More »
Synchrotron experiments allowed for a unique diagnosis of the heterogeneous physical degradation of fuel cell polymer membranes aged for 2500 hours in a real stack. The 3D mapping of the nanostructure is an efficient non-intrusive tool to assess the nature, localisation and degree of ageing, ... More »
Contact : Dorian Gaboriau
Dorian Gaboriau, a PhD student working at SPrAM/LEMOH and SP2M/SiNaPS and co-funded by DGA and CEA, has been awarded the NanoART monthly prize in October 2014.   NanoART is a Nano Imagery contest sponsored by nRai®, and organized in Grenoble by the ... More »
Contact : Pascale Maldivi
The valorization of CO2 to yield new carbonated molecules such as CH4 is a worldwide Graal, because of its huge potential in terms of renewable energy, while being a most difficult task. Indeed its reduction necessitates the activation of very stable bonds. The new complex designed by the group of ... More »
Contact : Damien JOLY
Damien JOLY, post-doct at SPrAM/LEMOH, has been awarded with the best poster prize in the DSSC categories at HOPV-14.   This conference was held at Lausanne in Switzerland in May with more than 660 participants. The best poster prize was awarded to Damien by professor Michael ... More »
Contact : Loic Leroy
Cyril Herrier, a post-doc fellow of the labex ARCANE, working at SPrAM/CREAB in collaboration with LETI/DTBS has been awarded the NanoART monthly prize in March 2014.   NanoART is a Nano Imagery contest sponsored by nRai®, and organized in Grenoble by the Nanoscience ... More »
The DNA molecule, which is the support of the genetic information, is continuously altered within cells by endogenous and exogenous processes. Among these reactions that alter the structure of the biopolymer, the hydrolytic reactions are the most common. The latter processes lead to loss or ... More »
Lithium ion batteries (LIB) are considered as prime candidates for electric vehicles. Among them, batteries with silicon nanoparticles (SiNPs) based negative electrode are very promising, thanks to their important energy storage capacity, ten times higher than the current ones. But their low ... More »
Contact : Stefano Mossa
Performances of the membrane-electrode assembly in polymer electrolyte fuel cells strongly depend on the features of the catalyst layer. This is a complex interface region which forms during the fabrication process, when the ionomer mixes with carbon supported platinum nanoparticles, ... More »
MRI is a non-invasive diagnostic tool providing high-resolution anatomical images consisting of 3D maps of the relaxation rates of the hydrogen nuclei in the body. However, its potential for molecular or functional imaging is limited by the low sensitivity of these rates to natural variation ... More »
Contact : Sylvie Sauvaigo
Sylvie Sauvaigo just received the prize in 2013 national contest for the creation of innovative companies. On Tuesday, July 2, 2013, Genevieve Fioraso chaired the ceremony national contest to support the creation of innovative companies. Created by the Ministry of Higher Education and Research in ... More »
The article entitled: "Amorphous Zinc Stannate (Zn2SnO4) Nanofibers Networks as photoelectrodes for Organic Dye-Sensitized Solar Cells", signed by the SPrAM, the SCIB and two Korean laboratories is published as front cover of the latest issue of Advanced Functional ... More »
Frédéric Chadezon of INAC/SPRAM was elected in April 2013 by the Steering Committee of AMPEA (Advanced Materials and Processes for Energy Applications) to coordinate  this basic research program in the framework of the European Alliance for Energy Research (EERA, ... More »
Contact : Saïd Sadki
A dense forest of nanotrees is the secret for an "ideal" electrodes surface in silicon supercapacitors, as DSM researchers demonstrated using long and highly-doped silicon nanowires. With this technology, components capable of delivering a surge of power within a few seconds could be ... More »
Contact: Jean Breton
DNA lesions are recognized within our cells by a myriad of proteins playing key roles in important processes such as DNA repair or modulation of gene expression. The team “Lésions des Acides Nucléiques” (DSM/INAC/SCIB) recently optimized baits aimed at catching and ... More »
HAL publications
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 Prix - Rodrigo Newell Electrochimie
Graphene as conductive additive: strong enhancement of the performances of silicon nanoparticle based Li-ion battery anodes
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Sugars increase drug delivery in the liver
Biochemistry Laboratory (CREAB)
Traps for proteins associated with DNA damage
Two prizes for Sylvie Sauvaigo and the LXRepair start-up
New organic dyes and nanostructured electrodes for applications in dye sensitized solar cells.
Inhomogeneous Transport in Model Hydrated Polymer Electrolyte Supported Ultra-Thin Films
Gadolinium chelates confined in silica nanoparticles for high contrast in Magnetic Resonance Imaging (MRI)
Gadolinium chelates confined in silica nanoparticles for high contrast in Magnetic Resonance Imaging (MRI)
Coordination of European basic research program for energy
New 3D symmetric micro-supercapacitors
The best poster prize in the DSSC categories at HOPV-14
Cyril Herrier awarded March 2014 NanoART prize
A new class of complexes effective in the reduction of CO2
Diagnosis of heterogeneous fuel cell membrane degradation
Dorian GABORIAU awarded October 2014 NanoART prize
Loiuis Vaure awarded December 2014 NanoART prize
Dorian GABORIAU awarded 2014 NanoART prize
Melanin synthesis: a paradoxical effect against UV
Jinhyung PARK awarded February 2015 NanoART prize
Chemical design of Copper chelators inspired by biological transporters for medicinal applications
New alga-like graphene morphology for the design of high performance supercapacitor devices
Heat transport in glasses and superlattices
Molecular Systems and Nanomaterials for Energy and Health (SyMMES)
Heterogeneous dynamics of water in soft confinement
Ultracapacitors with highly doped silicon nanowires electrodes
Mixtures effects in the genotoxicity of pollutants: when 1+1 is not 2
Li-rich lamellar oxides: zooming in, zooming out !
The Anion Effect on Li+ Ion Coordination Structure in Ethylene Carbonate Solutions
Chemistry-Biology Interface for environment, health and toxicology  (CIBEST)
Synthesis, Structure and Properties of Functional Materials (STEP)
Design of molecular architectures and electronic processes (CAMPE)
Design of molecular architectures and electronic processes (CAMPE)
Design of molecular architectures and electronic processes (CAMPE)
Design of molecular architectures and electronic processes (CAMPE)
Nanotweezers and their remote actuation by magnetic fields


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